| 1 |  |  | Juan Ayuso | UAE Team Emirates | 28:41:24h |
| 2 |  |  | Filippo Ganna | Ineos Grenadiers | +35s |
| 3 |  | | Antonio Tiberi | Bahrain Victorious | +36s |
| 4 |  |  | Derek Gee | Israel - Premier Tech | +42s |
| 5 |  |  | Jai Hindley | Red Bull–Bora–Hansgrohe | +53s |
| 6 |  |  | Thomas Pidcock | Q36.5 Pro Cycling Team | +56s |
| 7 |  | | Mikel Landa | Soudal - Quick Step | +1:05m |
| 8 |  | | David De la Cruz | Q36.5 Pro Cycling Team | +1:32m |
| 9 |  | | Pello Bilbao | Bahrain Victorious | +1:32m |
| 10 |  | | Mattia Cattaneo | Soudal - Quick Step | +1:38m |
| 11 |  |  | Tobias Johannessen | Uno-X Mobility | +1:46m |
| 12 |  |  | Kevin Vauquelin | Arkéa - B&B Hotels | +1:52m |
| 13 |  | | Giulio Ciccone | Lidl - Trek | +1:58m |
| 14 |  | | Simon Yates | Team Visma / Lease a Bike | +2:04m |
| 15 |  | | Romain Grégoire | Groupama - FDJ | +2:05m |
| 16 |  | | Adam Yates | UAE Team Emirates | +2:05m |
| 17 |  | | Davide Piganzoli | Team Polti VisitMalta | +2:11m |
| 18 |  |  | Richard Carapaz | EF Education-EasyPost | +2:26m |
| 19 |  |  | Isaac del Toro | UAE Team Emirates | +2:33m |
| 20 |  |  | Einer Augusto Rubio | Movistar Team | +2:33m |
| 21 |  | | Lorenzo Fortunato | XDS Astana Team | +2:40m |
| 22 |  | | Alessandro Pinarello | VF Group - Bardiani CSF - Faizanè | +2:41m |
| 23 |  |  | Marc Hirschi | Tudor Pro Cycling Team | +2:48m |
| 24 |  |  | Ben Healy | EF Education-EasyPost | +2:54m |
| 25 |  | | Filippo Zana | Team Jayco AlUla | +3:01m |
| 26 |  | | Simone Velasco | XDS Astana Team | +3:10m |
| 27 |  | | Samuel Kajamini Florian | XDS Astana Team | +3:26m |
| 28 |  | | Jon Izaguirre | Cofidis | +3:27m |
| 29 |  | | Alex Aranburu | Cofidis | +3:28m |
| 30 |  | | Filippo Fiorelli | VF Group - Bardiani CSF - Faizanè | +3:44m |
| 31 |  | | Andrea Vendrame | Decathlon AG2R La Mondiale Team | +4:07m |
| 32 |  | | Nairo Quintana Rojas | Movistar Team | +4:08m |
| 33 |  | | Nicola Conci | XDS Astana Team | +4:26m |
| 34 |  | | Christopher Hamilton | Team Picnic PostNL | +4:47m |
| 35 |  | | Valentin Madouas | Groupama - FDJ | +5:24m |
| 36 |  | | Johannes Staune-Mittet | Decathlon AG2R La Mondiale Team | +5:25m |
| 37 |  | | Nicolas Prodhomme | Decathlon AG2R La Mondiale Team | +5:31m |
| 38 |  | | Valentin Paret-Peintre | Soudal - Quick Step | +5:32m |
| 39 |  | | Quentin Pacher | Groupama - FDJ | +5:40m |
| 40 |  | | Esteban Chaves | EF Education-EasyPost | +6:10m |
| 41 |  | | Brandon Smith Rivera | Ineos Grenadiers | +6:22m |
| 42 |  | | Luca Covili | VF Group - Bardiani CSF - Faizanè | +6:29m |
| 43 |  |  | Jonas Rutsch | Intermarché - Wanty | +6:43m |
| 44 |  |  | Jasper Stuyven | Lidl - Trek | +6:54m |
| 45 |  | | Fredrik Dversnes | Uno-X Mobility | +7:05m |
| 46 |  | | Laurens De Plus | Ineos Grenadiers | +8:39m |
| 47 |  | | Cristian Rodriguez Martin | Arkéa - B&B Hotels | +9:28m |
| 48 |  | | Roger Adriá | Red Bull–Bora–Hansgrohe | +10:21m |
| 49 |  |  | Gijs Leemreize | Team Picnic PostNL | +10:48m |
| 50 |  | | Mathieu Van der Poel | Alpecin - Deceuninck | +11:26m |
| 51 |  | | Davide Formolo | Movistar Team | +12:10m |
| 52 |  |  | Orluis Aular | Movistar Team | +13:46m |
| 53 |  | | Mark Donovan | Q36.5 Pro Cycling Team | +14:44m |
| 54 |  | | Gianni Vermeersch | Alpecin - Deceuninck | +16:23m |
| 55 |  | | Rick Pluimers | Tudor Pro Cycling Team | +17:28m |
| 56 |  |  | Attila Valter | Team Visma / Lease a Bike | +17:38m |
| 57 |  | | Hannes Wilksch | Tudor Pro Cycling Team | +18:38m |
| 58 |  | | Francesco Busatto | Intermarché - Wanty | +19:39m |
| 59 |  | | Mirco Maestri | Team Polti VisitMalta | +19:56m |
| 60 |  |  | Felix Großschartner | UAE Team Emirates | +20:30m |
| 61 |  | | Alessandro Tonelli | Team Polti VisitMalta | +21:14m |
| 62 |  | | Gianni Moscon | Red Bull–Bora–Hansgrohe | +21:19m |
| 63 |  | | Manuele Tarozzi | VF Group - Bardiani CSF - Faizanè | +23:21m |
| 64 |  | | Matteo Scalco | VF Group - Bardiani CSF - Faizanè | +24:34m |
| 65 |  | | Lorenzo Germani | Groupama - FDJ | +24:49m |
| 66 |  | | Damiano Caruso | Bahrain Victorious | +24:54m |
| 67 |  | | Jorge Arcas | Movistar Team | +25:05m |
| 68 |  |  | Lawrence Warbasse | Tudor Pro Cycling Team | +25:27m |
| 69 |  | | Steven Kruijswijk | Team Visma / Lease a Bike | +25:49m |
| 70 |  | | Paul Ourselin | Cofidis | +26:33m |
| 71 |  | | Benjamin Thomas | Cofidis | +26:43m |
| 72 |  |  | Rafał Majka | UAE Team Emirates | +26:52m |
| 73 |  | | Anthony Delaplace | Arkéa - B&B Hotels | +26:53m |
| 74 |  |  | Gal Glivar | Alpecin - Deceuninck | +27:36m |
| 75 |  | | Jasha Sütterlin | Team Jayco AlUla | +27:58m |
| 76 |  | | Marco Frigo | Israel - Premier Tech | +29:34m |
| 77 |  | | Connor Swift | Ineos Grenadiers | +30:11m |
| 78 |  | | Anders Johannessen | Uno-X Mobility | +30:22m |
| 79 |  | | Florian Stork | Tudor Pro Cycling Team | +31:09m |
| 80 |  | | Clément Venturini | Arkéa - B&B Hotels | +31:28m |
| 81 |  | | Kevin Colleoni | Intermarché - Wanty | +31:48m |
| 82 |  | | Tim van Dijke | Red Bull–Bora–Hansgrohe | +31:52m |
| 83 |  | | Filip Maciejuk | Red Bull–Bora–Hansgrohe | +32:13m |
| 84 |  |  | Jakob Fuglsang | Israel - Premier Tech | +33:24m |
| 85 |  | | Casper van Uden | Team Picnic PostNL | +33:31m |
| 86 |  | | Dries De Bondt | Decathlon AG2R La Mondiale Team | +33:42m |
| 87 |  | | Davide Toneatti | XDS Astana Team | +33:44m |
| 88 |  | | Dylan van Baarle | Team Visma / Lease a Bike | +34:35m |
| 89 |  | | Robert Stannard | Bahrain Victorious | +34:42m |
| 90 |  | | Casper Pedersen | Soudal - Quick Step | +34:51m |
| 91 |  | | Paul Magnier | Soudal - Quick Step | +35:08m |
| 92 |  | | Francisco Muñoz | Team Polti VisitMalta | +35:11m |
| 93 |  | | Samuele Battistella | EF Education-EasyPost | +35:23m |
| 94 |  | | Jonas Koch | Red Bull–Bora–Hansgrohe | +36:05m |
| 95 |  | | Jan Maas | Cofidis | +37:47m |
| 96 |  | | Olav Kooij | Team Visma / Lease a Bike | +37:51m |
| 97 |  | | William Blume Levy | Uno-X Mobility | +38:10m |
| 98 |  | | Kamiel Bonneu | Intermarché - Wanty | +39:09m |
| 99 |  |  | Natnael Tesfazion | Movistar Team | +40:30m |
| 100 |  | | Dorian Godon | Decathlon AG2R La Mondiale Team | +41:37m |
| 101 |  | | Paul Penhoët | Groupama - FDJ | +41:42m |
| 102 |  | | Enzo Leijnse | Team Picnic PostNL | +42:46m |
| 103 |  | | Ådne Holter | Uno-X Mobility | +43:04m |
| 104 |  |  | Toms Skujiņš | Lidl - Trek | +44:15m |
| 105 |  | | Clément Russo | Groupama - FDJ | +44:28m |
| 106 |  | | Giovanni Lonardi | Team Polti VisitMalta | +45:48m |
| 107 |  | | Mathis Le Berre | Arkéa - B&B Hotels | +46:28m |
| 108 |  | | Davide Bais | Team Polti VisitMalta | +46:43m |
| 109 |  | | Andrea Pietrobon | Team Polti VisitMalta | +47:52m |
| 110 |  | | Magnus Cort | Uno-X Mobility | +48:35m |
| 111 |  | | Pepijn Reinderink | Soudal - Quick Step | +48:47m |
| 112 |  | | Amanuel Ghebreigzabhier | Lidl - Trek | +50:15m |
| 113 |  | | Enrico Zanocello | VF Group - Bardiani CSF - Faizanè | +51:15m |
| 114 |  | | Xandro Meurisse | Alpecin - Deceuninck | +52:27m |
| 115 |  |  | Samuel Gaze | Alpecin - Deceuninck | +52:33m |
| 116 |  | | Lucas Hamilton | Ineos Grenadiers | +53:42m |
| 117 |  |  | Josef Černý | Soudal - Quick Step | +53:45m |
| 118 |  |  | Jake Stewart | Israel - Premier Tech | +53:49m |
| 119 |  | | Damien Howson | Q36.5 Pro Cycling Team | +54:40m |
| 120 |  |  | Fran Miholjević | Bahrain Victorious | +57:53m |
| 121 |  | | Maikel Zijlaard | Tudor Pro Cycling Team | +58:23m |
| 122 |  | | Niklas Märkl | Team Picnic PostNL | +59:53m |
| 123 |  | | Andrea Pasqualon | Bahrain Victorious | +1:02:15h |
| 124 |  | | Tord Gudmestad | Decathlon AG2R La Mondiale Team | +1:02:18h |
| 125 |  | | Patrick Gamper | Team Jayco AlUla | +1:02:31h |
| 126 |  | | Luka Mezgec | Team Jayco AlUla | +1:04:45h |
| 127 |  | | Amaury Capiot | Arkéa - B&B Hotels | +1:05:20h |
| 128 |  |  | Nadav Raisberg | Israel - Premier Tech | +1:05:26h |
| 129 |  | | Bryan Coquard | Cofidis | +1:06:11h |
| 130 |  | | Edward Theuns | Lidl - Trek | +1:06:16h |
| 131 |  | | Daniel McLay | Team Visma / Lease a Bike | +1:06:22h |
| 132 |  | | Valentin Ferron | Cofidis | +1:07:33h |
| 133 |  | | Elmar Reinders | Team Jayco AlUla | +1:08:38h |
| 134 |  | | Alexander Krieger | Tudor Pro Cycling Team | +1:11:20h |
| 135 |  | | Jonathan Milan | Lidl - Trek | +1:11:58h |
| 136 |  | | Sam Bennett | Decathlon AG2R La Mondiale Team | +1:12:58h |
| 137 |  | | Dylan Groenewegen | Team Jayco AlUla | +1:15:21h |
| 138 |  | | Søren Wærenskjold | Uno-X Mobility | +1:15:29h |
